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En esta área se investigan características de moléculas activas relacionadas con el sueño con el propósito de desarrollar nuevas formulaciones.
EDUCATION
Bachelor’s Degree: Ciències Químiques (UAB-February 2001)
Master’s Degree: Química Orgànica estructural (UAB-November 2002)
Title: Synthesis of a,a’-bis(trifluoromethyl)-9,10-anthracendimethanol (ABTE). Enantioselective synthesis”.
Director: Dr. Albert Virgili Moyà
Doctor’s Degree: Química Orgànica estructural (UAB-July 2006)
Research: Stereoselective synthesis of new chiral solvating agents (CSA) and the study, through NMR, of the chiral recognition of a range of chiral drugs.
Director: Dr. Albert Virgili i Moyà
WORK EXPERIENCE
Manager in Synthesis content, in Integrity database.
Thomson Reuters October 2007- Currently.
Collaboration, in the I+D laboratory of a pharmaceutical company, on the enhancement of the synthesis of a drug.
Finnovequim, S.L. October 2006-October 2007.
During the doctorate, I have been training in bibliographic search, stereoselective synthesis, analysis for CG, IR, EM, a broad use of HPLC and NMR, and specific computer programs as ChemOffice, SciFinder, Winnmr, Topspin.
Organic Chemistry Unit, UAB. December 2000- September 2005.
Study of CSAs through solid state NMR.
Organic chemistry and Biology Dept., Science faculty, UNED. January- February 2004.
Collaboration, in the I+D laboratory of a pharmaceutical company, on the enhancement of the synthesis of a drug and its scale up.
Kern Pharma, S.L. August 2000-Desember 2000.
Laboratory auxiliary in a pharmaceutical laboratory of analysis.
Seid, S.A., January 2000- February 2000.
Collaboration in tasks of research in the synthesis of new chiral solvating agents, NMR studies and the use of the HPLC.
Organic Chemistry unit, UAB. July-September 1998, July-September 1999.
Other activities: Secretary in a psychologist’s office (1993-1994), polisomnographic studies in a private clinic (1995), teaching (2001-2005).
PUBLICATIONS
Title :“Synthesis and structural study of the enantiomers of α,α’-bis(trifluoromethyl)-10,10’-(9,9’-bianthryl)dimethanol as a chiral solvating agent”.
Sánchez-Aris, M., Estivill, C.; Virgili, A. Tetrahedron: Assymetry, 2003, 14, 3129.
Title:”α,α’-bis(trifluoromethyl)-9,10-anthracenedimethanol: enantiosesective synthesis and bidentate complexes with benzenedimethanols”.
Estivill, C.; Ivanov, P. M.; Pomares, M.; Sánchez-Arís, M.; Virgili, A.Tetrahedron: Assymetry, 2004, 15, 1431.
Title:”(R,R)-α,α’-bis(trifluoromethyl)-9,10-anthracenedimethanol: a chiral solvating agent for enantiomeric resolution of β-dicarbonyl compounds”.
Comelles, J.; Estivill, C.; Moreno-Mañas, M.; Virgili, A.; Vallribera, A. Tetrahedron, 2004, 60, 11541.
Title: ”The bidentate complexes of (R,R)- and meso-a,a’-bis(trifluoromethyl)-9,10-anthracenedimetanol with cis-1-amino-2-indanol”.
Estivill, C.; Pomares, M.; Kotev, M.; Ivanov, P.; Virgili, A. Tetrahedron: Asymmetry, 2005, 16, 2993.
Title: ”Computational (MM, MD and MKMM) study o bidentate complexes of (R,R)- and meso-a,a’-bis(trifluoromethyl)-9,10-anthracendimethanol with cis-1-amino-2-indanol”.
Kotev, M. I., Ivanov, P. M.; Virgili, A.; Estivill, C. J. Mol. Struct., In press.
CONVENTION ATTENDANCE
Advanced course of Nuclear Magnetic Ressonance. Summer course (2001)
Patents and utility models course (2002)
XIX Biennial meeting of Organic Chemistry. Oral Communication: “El a,a’-bis(trifluorometilo)-9,10-antracenodimetanol, un nuevo agente de solvatación”. (2002).
I Biennial meeting of the specialized group of NMR of the RSEQ. Poster: “Asociación entre el a,a’-bis(trifluorometilo)-9,10-antracenodimetanol y benzendimetanol. Un caso de complejos bimodales”. (2002)
New challenges for the NMR in the pharma and chemical industry (2003)
Conference of the specialized group of NMR of the RSEQ (2003).
II Biennial meeting of the specialized group of NMR of the RSEQ (2004)
NMR in drug discovery (2004)
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